********************************************************************* * LD Score Regression (LDSC) * Version 1.0.0 * (C) 2014-2015 Brendan Bulik-Sullivan and Hilary Finucane * Broad Institute of MIT and Harvard / MIT Department of Mathematics * GNU General Public License v3 ********************************************************************* Call: ./ldsc.py \ --print-snps /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.22.snp \ --ld-wind-cm 1.0 \ --out all_da_open_results/train_models/clusters_12-cluster_1.22 \ --bfile /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.22 \ --annot all_da_open_results/train_models/clusters_12-cluster_1.22.annot.gz \ --l2 Beginning analysis at Wed Nov 1 00:12:18 2017 Read list of 141123 SNPs from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.22.bim Read 1 annotations for 141123 SNPs from all_da_open_results/train_models/clusters_12-cluster_1.22.annot.gz Read list of 489 individuals from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.22.fam Reading genotypes from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.22.bed Estimating LD Score. Reading list of 20106 SNPs for which to print LD Scores from /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.22.snp After merging with --print-snps, LD Scores for 17261 SNPs will be printed. Writing LD Scores for 17261 SNPs to all_da_open_results/train_models/clusters_12-cluster_1.22.l2.ldscore.gz Summary of LD Scores in all_da_open_results/train_models/clusters_12-cluster_1.22.l2.ldscore.gz MAF L2 mean 0.2359 1.3578 std 0.1442 2.3495 min 0.0051 -0.1216 25% 0.1084 0.0000 50% 0.2280 0.1752 75% 0.3579 1.7178 max 0.5000 15.9037 MAF/LD Score Correlation Matrix MAF L2 MAF 1.00 0.08 L2 0.08 1.00 Annotation Correlation Matrix SPECIFIC_PEAK_INTERSECT SPECIFIC_PEAK_INTERSECT 1.0 Annotation Matrix Column Sums SPECIFIC_PEAK_INTERSECT 1843 Summary of Annotation Matrix Row Sums count 141123.0000 mean 0.0131 std 0.1135 min 0.0000 25% 0.0000 50% 0.0000 75% 0.0000 max 1.0000 Analysis finished at Wed Nov 1 00:22:07 2017 Total time elapsed: 9.0m:48.82s