********************************************************************* * LD Score Regression (LDSC) * Version 1.0.0 * (C) 2014-2015 Brendan Bulik-Sullivan and Hilary Finucane * Broad Institute of MIT and Harvard / MIT Department of Mathematics * GNU General Public License v3 ********************************************************************* Call: ./ldsc.py \ --print-snps /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.8.snp \ --ld-wind-cm 1.0 \ --out all_da_open_results/train_models/clusters_17-cluster_2.8 \ --bfile /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.8 \ --annot all_da_open_results/train_models/clusters_17-cluster_2.8.annot.gz \ --l2 Beginning analysis at Tue Oct 31 20:30:25 2017 Read list of 549971 SNPs from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.8.bim Read 1 annotations for 549971 SNPs from all_da_open_results/train_models/clusters_17-cluster_2.8.annot.gz Read list of 489 individuals from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.8.fam Reading genotypes from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.8.bed Estimating LD Score. Reading list of 75345 SNPs for which to print LD Scores from /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.8.snp After merging with --print-snps, LD Scores for 65167 SNPs will be printed. Writing LD Scores for 65167 SNPs to all_da_open_results/train_models/clusters_17-cluster_2.8.l2.ldscore.gz Summary of LD Scores in all_da_open_results/train_models/clusters_17-cluster_2.8.l2.ldscore.gz MAF L2 mean 0.2368 0.4497 std 0.1438 1.2482 min 0.0051 -0.0945 25% 0.1094 0.0000 50% 0.2270 0.0243 75% 0.3599 0.2214 max 0.5000 17.0873 MAF/LD Score Correlation Matrix MAF L2 MAF 1.000 0.104 L2 0.104 1.000 Annotation Correlation Matrix SPECIFIC_PEAK_INTERSECT SPECIFIC_PEAK_INTERSECT 1.0 Annotation Matrix Column Sums SPECIFIC_PEAK_INTERSECT 2064 Summary of Annotation Matrix Row Sums count 549971.0000 mean 0.0038 std 0.0611 min 0.0000 25% 0.0000 50% 0.0000 75% 0.0000 max 1.0000 Analysis finished at Tue Oct 31 22:21:04 2017 Total time elapsed: 1.0h:50.0m:39.21s