********************************************************************* * LD Score Regression (LDSC) * Version 1.0.0 * (C) 2014-2015 Brendan Bulik-Sullivan and Hilary Finucane * Broad Institute of MIT and Harvard / MIT Department of Mathematics * GNU General Public License v3 ********************************************************************* Call: ./ldsc.py \ --print-snps /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.14.snp \ --ld-wind-cm 1.0 \ --out all_da_open_results/train_models/clusters_17-cluster_4.14 \ --bfile /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.14 \ --annot all_da_open_results/train_models/clusters_17-cluster_4.14.annot.gz \ --l2 Beginning analysis at Tue Oct 31 22:53:42 2017 Read list of 324698 SNPs from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.14.bim Read 1 annotations for 324698 SNPs from all_da_open_results/train_models/clusters_17-cluster_4.14.annot.gz Read list of 489 individuals from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.14.fam Reading genotypes from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.14.bed Estimating LD Score. Reading list of 45556 SNPs for which to print LD Scores from /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.14.snp After merging with --print-snps, LD Scores for 39504 SNPs will be printed. Writing LD Scores for 39504 SNPs to all_da_open_results/train_models/clusters_17-cluster_4.14.l2.ldscore.gz Summary of LD Scores in all_da_open_results/train_models/clusters_17-cluster_4.14.l2.ldscore.gz MAF L2 mean 0.2308 0.0655 std 0.1432 0.3219 min 0.0051 -0.0310 25% 0.1053 0.0000 50% 0.2188 0.0000 75% 0.3497 0.0081 max 0.5000 5.9166 MAF/LD Score Correlation Matrix MAF L2 MAF 1.0000 0.0878 L2 0.0878 1.0000 Annotation Correlation Matrix SPECIFIC_PEAK_INTERSECT SPECIFIC_PEAK_INTERSECT 1.0 Annotation Matrix Column Sums SPECIFIC_PEAK_INTERSECT 225 Summary of Annotation Matrix Row Sums count 324698.0000 mean 0.0007 std 0.0263 min 0.0000 25% 0.0000 50% 0.0000 75% 0.0000 max 1.0000 Analysis finished at Tue Oct 31 23:20:40 2017 Total time elapsed: 26.0m:57.96s