********************************************************************* * LD Score Regression (LDSC) * Version 1.0.0 * (C) 2014-2015 Brendan Bulik-Sullivan and Hilary Finucane * Broad Institute of MIT and Harvard / MIT Department of Mathematics * GNU General Public License v3 ********************************************************************* Call: ./ldsc.py \ --print-snps /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.3.snp \ --ld-wind-cm 1.0 \ --out all_da_open_results/train_models/clusters_2-cluster_1.3 \ --bfile /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.3 \ --annot all_da_open_results/train_models/clusters_2-cluster_1.3.annot.gz \ --l2 Beginning analysis at Tue Oct 31 17:27:55 2017 Read list of 706350 SNPs from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.3.bim Read 1 annotations for 706350 SNPs from all_da_open_results/train_models/clusters_2-cluster_1.3.annot.gz Read list of 489 individuals from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.3.fam Reading genotypes from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.3.bed Estimating LD Score. Reading list of 96664 SNPs for which to print LD Scores from /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.3.snp After merging with --print-snps, LD Scores for 83286 SNPs will be printed. Writing LD Scores for 83286 SNPs to all_da_open_results/train_models/clusters_2-cluster_1.3.l2.ldscore.gz Summary of LD Scores in all_da_open_results/train_models/clusters_2-cluster_1.3.l2.ldscore.gz MAF L2 mean 0.2395 1.0275 std 0.1436 2.0023 min 0.0051 -0.2687 25% 0.1145 0.0061 50% 0.2311 0.1490 75% 0.3630 1.1181 max 0.5000 19.9571 MAF/LD Score Correlation Matrix MAF L2 MAF 1.0000 0.0712 L2 0.0712 1.0000 Annotation Correlation Matrix SPECIFIC_PEAK_INTERSECT SPECIFIC_PEAK_INTERSECT 1.0 Annotation Matrix Column Sums SPECIFIC_PEAK_INTERSECT 5807 Summary of Annotation Matrix Row Sums count 706350.0000 mean 0.0082 std 0.0903 min 0.0000 25% 0.0000 50% 0.0000 75% 0.0000 max 1.0000 Analysis finished at Tue Oct 31 20:17:56 2017 Total time elapsed: 2.0h:50.0m:1.12s