********************************************************************* * LD Score Regression (LDSC) * Version 1.0.0 * (C) 2014-2015 Brendan Bulik-Sullivan and Hilary Finucane * Broad Institute of MIT and Harvard / MIT Department of Mathematics * GNU General Public License v3 ********************************************************************* Call: ./ldsc.py \ --print-snps /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.16.snp \ --ld-wind-cm 1.0 \ --out all_da_open_results/train_models/clusters_24-cluster_1.16 \ --bfile /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.16 \ --annot all_da_open_results/train_models/clusters_24-cluster_1.16.annot.gz \ --l2 Beginning analysis at Tue Oct 31 23:17:17 2017 Read list of 316981 SNPs from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.16.bim Read 1 annotations for 316981 SNPs from all_da_open_results/train_models/clusters_24-cluster_1.16.annot.gz Read list of 489 individuals from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.16.fam Reading genotypes from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.16.bed Estimating LD Score. Reading list of 44710 SNPs for which to print LD Scores from /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.16.snp After merging with --print-snps, LD Scores for 37656 SNPs will be printed. Writing LD Scores for 37656 SNPs to all_da_open_results/train_models/clusters_24-cluster_1.16.l2.ldscore.gz Summary of LD Scores in all_da_open_results/train_models/clusters_24-cluster_1.16.l2.ldscore.gz MAF L2 mean 0.2370 0.4906 std 0.1437 1.1221 min 0.0051 -0.0988 25% 0.1115 0.0000 50% 0.2290 0.0231 75% 0.3589 0.3599 max 0.5000 9.9565 MAF/LD Score Correlation Matrix MAF L2 MAF 1.0000 0.0253 L2 0.0253 1.0000 Annotation Correlation Matrix SPECIFIC_PEAK_INTERSECT SPECIFIC_PEAK_INTERSECT 1.0 Annotation Matrix Column Sums SPECIFIC_PEAK_INTERSECT 1625 Summary of Annotation Matrix Row Sums count 316981.0000 mean 0.0051 std 0.0714 min 0.0000 25% 0.0000 50% 0.0000 75% 0.0000 max 1.0000 Analysis finished at Wed Nov 1 00:05:37 2017 Total time elapsed: 48.0m:20.17s