********************************************************************* * LD Score Regression (LDSC) * Version 1.0.0 * (C) 2014-2015 Brendan Bulik-Sullivan and Hilary Finucane * Broad Institute of MIT and Harvard / MIT Department of Mathematics * GNU General Public License v3 ********************************************************************* Call: ./ldsc.py \ --print-snps /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.16.snp \ --ld-wind-cm 1.0 \ --out all_da_open_results/train_models/clusters_24-cluster_2.16 \ --bfile /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.16 \ --annot all_da_open_results/train_models/clusters_24-cluster_2.16.annot.gz \ --l2 Beginning analysis at Tue Oct 31 23:16:45 2017 Read list of 316981 SNPs from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.16.bim Read 1 annotations for 316981 SNPs from all_da_open_results/train_models/clusters_24-cluster_2.16.annot.gz Read list of 489 individuals from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.16.fam Reading genotypes from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.16.bed Estimating LD Score. Reading list of 44710 SNPs for which to print LD Scores from /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.16.snp After merging with --print-snps, LD Scores for 37656 SNPs will be printed. Writing LD Scores for 37656 SNPs to all_da_open_results/train_models/clusters_24-cluster_2.16.l2.ldscore.gz Summary of LD Scores in all_da_open_results/train_models/clusters_24-cluster_2.16.l2.ldscore.gz MAF L2 mean 0.2370 0.2111 std 0.1437 0.6436 min 0.0051 -0.0671 25% 0.1115 0.0000 50% 0.2290 0.0014 75% 0.3589 0.0682 max 0.5000 8.6740 MAF/LD Score Correlation Matrix MAF L2 MAF 1.000 0.012 L2 0.012 1.000 Annotation Correlation Matrix SPECIFIC_PEAK_INTERSECT SPECIFIC_PEAK_INTERSECT 1.0 Annotation Matrix Column Sums SPECIFIC_PEAK_INTERSECT 823 Summary of Annotation Matrix Row Sums count 316981.0000 mean 0.0026 std 0.0509 min 0.0000 25% 0.0000 50% 0.0000 75% 0.0000 max 1.0000 Analysis finished at Tue Oct 31 23:35:48 2017 Total time elapsed: 19.0m:2.88s