********************************************************************* * LD Score Regression (LDSC) * Version 1.0.0 * (C) 2014-2015 Brendan Bulik-Sullivan and Hilary Finucane * Broad Institute of MIT and Harvard / MIT Department of Mathematics * GNU General Public License v3 ********************************************************************* Call: ./ldsc.py \ --print-snps /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.20.snp \ --ld-wind-cm 1.0 \ --out all_da_open_results/train_models/clusters_26-cluster_1.20 \ --bfile /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.20 \ --annot all_da_open_results/train_models/clusters_26-cluster_1.20.annot.gz \ --l2 Beginning analysis at Tue Oct 31 23:57:20 2017 Read list of 221626 SNPs from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.20.bim Read 1 annotations for 221626 SNPs from all_da_open_results/train_models/clusters_26-cluster_1.20.annot.gz Read list of 489 individuals from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.20.fam Reading genotypes from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.20.bed Estimating LD Score. Reading list of 36301 SNPs for which to print LD Scores from /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.20.snp After merging with --print-snps, LD Scores for 31359 SNPs will be printed. Writing LD Scores for 31359 SNPs to all_da_open_results/train_models/clusters_26-cluster_1.20.l2.ldscore.gz Summary of LD Scores in all_da_open_results/train_models/clusters_26-cluster_1.20.l2.ldscore.gz MAF L2 mean 0.2336 0.1620 std 0.1437 0.5340 min 0.0051 -0.0720 25% 0.1063 0.0000 50% 0.2219 0.0000 75% 0.3569 0.0489 max 0.5000 6.7477 MAF/LD Score Correlation Matrix MAF L2 MAF 1.0000 0.0589 L2 0.0589 1.0000 Annotation Correlation Matrix SPECIFIC_PEAK_INTERSECT SPECIFIC_PEAK_INTERSECT 1.0 Annotation Matrix Column Sums SPECIFIC_PEAK_INTERSECT 408 Summary of Annotation Matrix Row Sums count 221626.0000 mean 0.0018 std 0.0429 min 0.0000 25% 0.0000 50% 0.0000 75% 0.0000 max 1.0000 Analysis finished at Wed Nov 1 00:08:37 2017 Total time elapsed: 11.0m:17.57s