********************************************************************* * LD Score Regression (LDSC) * Version 1.0.0 * (C) 2014-2015 Brendan Bulik-Sullivan and Hilary Finucane * Broad Institute of MIT and Harvard / MIT Department of Mathematics * GNU General Public License v3 ********************************************************************* Call: ./ldsc.py \ --print-snps /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.5.snp \ --ld-wind-cm 1.0 \ --out all_da_open_results/train_models/clusters_4-cluster_4.5 \ --bfile /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.5 \ --annot all_da_open_results/train_models/clusters_4-cluster_4.5.annot.gz \ --l2 Beginning analysis at Tue Oct 31 18:31:31 2017 Read list of 633015 SNPs from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.5.bim Read 1 annotations for 633015 SNPs from all_da_open_results/train_models/clusters_4-cluster_4.5.annot.gz Read list of 489 individuals from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.5.fam Reading genotypes from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.5.bed Estimating LD Score. Reading list of 88059 SNPs for which to print LD Scores from /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.5.snp After merging with --print-snps, LD Scores for 74950 SNPs will be printed. Writing LD Scores for 74950 SNPs to all_da_open_results/train_models/clusters_4-cluster_4.5.l2.ldscore.gz Summary of LD Scores in all_da_open_results/train_models/clusters_4-cluster_4.5.l2.ldscore.gz MAF L2 mean 0.2353 0.1386 std 0.1428 0.4870 min 0.0051 -0.0651 25% 0.1104 0.0000 50% 0.2260 0.0012 75% 0.3558 0.0464 max 0.5000 10.7184 MAF/LD Score Correlation Matrix MAF L2 MAF 1.0000 0.0223 L2 0.0223 1.0000 Annotation Correlation Matrix SPECIFIC_PEAK_INTERSECT SPECIFIC_PEAK_INTERSECT 1.0 Annotation Matrix Column Sums SPECIFIC_PEAK_INTERSECT 784 Summary of Annotation Matrix Row Sums count 633015.0000 mean 0.0012 std 0.0352 min 0.0000 25% 0.0000 50% 0.0000 75% 0.0000 max 1.0000 Analysis finished at Tue Oct 31 19:27:04 2017 Total time elapsed: 55.0m:32.74s