********************************************************************* * LD Score Regression (LDSC) * Version 1.0.0 * (C) 2014-2015 Brendan Bulik-Sullivan and Hilary Finucane * Broad Institute of MIT and Harvard / MIT Department of Mathematics * GNU General Public License v3 ********************************************************************* Call: ./ldsc.py \ --print-snps /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.3.snp \ --ld-wind-cm 1.0 \ --out all_da_open_results/train_models/clusters_5-cluster_2.3 \ --bfile /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.3 \ --annot all_da_open_results/train_models/clusters_5-cluster_2.3.annot.gz \ --l2 Beginning analysis at Tue Oct 31 17:27:53 2017 Read list of 706350 SNPs from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.3.bim Read 1 annotations for 706350 SNPs from all_da_open_results/train_models/clusters_5-cluster_2.3.annot.gz Read list of 489 individuals from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.3.fam Reading genotypes from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.3.bed Estimating LD Score. Reading list of 96664 SNPs for which to print LD Scores from /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.3.snp After merging with --print-snps, LD Scores for 83286 SNPs will be printed. Writing LD Scores for 83286 SNPs to all_da_open_results/train_models/clusters_5-cluster_2.3.l2.ldscore.gz Summary of LD Scores in all_da_open_results/train_models/clusters_5-cluster_2.3.l2.ldscore.gz MAF L2 mean 0.2395 1.1974 std 0.1436 1.7773 min 0.0051 -0.1211 25% 0.1145 0.1159 50% 0.2311 0.5046 75% 0.3630 1.4977 max 0.5000 18.1503 MAF/LD Score Correlation Matrix MAF L2 MAF 1.0000 0.0855 L2 0.0855 1.0000 Annotation Correlation Matrix SPECIFIC_PEAK_INTERSECT SPECIFIC_PEAK_INTERSECT 1.0 Annotation Matrix Column Sums SPECIFIC_PEAK_INTERSECT 7515 Summary of Annotation Matrix Row Sums count 706350.0000 mean 0.0106 std 0.1026 min 0.0000 25% 0.0000 50% 0.0000 75% 0.0000 max 1.0000 Analysis finished at Tue Oct 31 20:08:07 2017 Total time elapsed: 2.0h:40.0m:14.19s