********************************************************************* * LD Score Regression (LDSC) * Version 1.0.0 * (C) 2014-2015 Brendan Bulik-Sullivan and Hilary Finucane * Broad Institute of MIT and Harvard / MIT Department of Mathematics * GNU General Public License v3 ********************************************************************* Call: ./ldsc.py \ --print-snps /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.6.snp \ --ld-wind-cm 1.0 \ --out all_da_open_results/train_models/clusters_1-cluster_3.6 \ --bfile /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.6 \ --annot all_da_open_results/train_models/clusters_1-cluster_3.6.annot.gz \ --l2 Beginning analysis at Tue Oct 31 19:09:44 2017 Read list of 664016 SNPs from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.6.bim Read 1 annotations for 664016 SNPs from all_da_open_results/train_models/clusters_1-cluster_3.6.annot.gz Read list of 489 individuals from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.6.fam Reading genotypes from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.6.bed Estimating LD Score. Reading list of 91491 SNPs for which to print LD Scores from /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.6.snp After merging with --print-snps, LD Scores for 80218 SNPs will be printed. Writing LD Scores for 80218 SNPs to all_da_open_results/train_models/clusters_1-cluster_3.6.l2.ldscore.gz Summary of LD Scores in all_da_open_results/train_models/clusters_1-cluster_3.6.l2.ldscore.gz MAF L2 mean 0.2331 0.1025 std 0.1441 0.3524 min 0.0051 -0.0556 25% 0.1074 0.0000 50% 0.2219 0.0005 75% 0.3558 0.0338 max 0.5000 8.5761 MAF/LD Score Correlation Matrix MAF L2 MAF 1.000 0.005 L2 0.005 1.000 Annotation Correlation Matrix SPECIFIC_PEAK_INTERSECT SPECIFIC_PEAK_INTERSECT 1.0 Annotation Matrix Column Sums SPECIFIC_PEAK_INTERSECT 562 Summary of Annotation Matrix Row Sums count 664016.0000 mean 0.0008 std 0.0291 min 0.0000 25% 0.0000 50% 0.0000 75% 0.0000 max 1.0000 Analysis finished at Tue Oct 31 21:32:09 2017 Total time elapsed: 2.0h:22.0m:24.2s