********************************************************************* * LD Score Regression (LDSC) * Version 1.0.0 * (C) 2014-2015 Brendan Bulik-Sullivan and Hilary Finucane * Broad Institute of MIT and Harvard / MIT Department of Mathematics * GNU General Public License v3 ********************************************************************* Call: ./ldsc.py \ --print-snps /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.1.snp \ --ld-wind-cm 1.0 \ --out all_da_open_results/train_models/clusters_11-cluster_5.1 \ --bfile /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.1 \ --annot all_da_open_results/train_models/clusters_11-cluster_5.1.annot.gz \ --l2 Beginning analysis at Tue Oct 31 17:27:10 2017 Read list of 779354 SNPs from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.1.bim Read 1 annotations for 779354 SNPs from all_da_open_results/train_models/clusters_11-cluster_5.1.annot.gz Read list of 489 individuals from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.1.fam Reading genotypes from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.1.bed Estimating LD Score. Reading list of 116564 SNPs for which to print LD Scores from /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.1.snp After merging with --print-snps, LD Scores for 98690 SNPs will be printed. Writing LD Scores for 98690 SNPs to all_da_open_results/train_models/clusters_11-cluster_5.1.l2.ldscore.gz Summary of LD Scores in all_da_open_results/train_models/clusters_11-cluster_5.1.l2.ldscore.gz MAF L2 mean 0.2329 0.5731 std 0.1442 1.2315 min 0.0051 -0.0962 25% 0.1056 0.0121 50% 0.2219 0.1036 75% 0.3548 0.5514 max 0.5000 14.8287 MAF/LD Score Correlation Matrix MAF L2 MAF 1.0000 0.0536 L2 0.0536 1.0000 Annotation Correlation Matrix SPECIFIC_PEAK_INTERSECT SPECIFIC_PEAK_INTERSECT 1.0 Annotation Matrix Column Sums SPECIFIC_PEAK_INTERSECT 4555 Summary of Annotation Matrix Row Sums count 779354.0000 mean 0.0058 std 0.0762 min 0.0000 25% 0.0000 50% 0.0000 75% 0.0000 max 1.0000 Analysis finished at Tue Oct 31 19:41:29 2017 Total time elapsed: 2.0h:14.0m:19.28s