********************************************************************* * LD Score Regression (LDSC) * Version 1.0.0 * (C) 2014-2015 Brendan Bulik-Sullivan and Hilary Finucane * Broad Institute of MIT and Harvard / MIT Department of Mathematics * GNU General Public License v3 ********************************************************************* Call: ./ldsc.py \ --print-snps /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.21.snp \ --ld-wind-cm 1.0 \ --out all_da_open_results/train_models/clusters_12-cluster_5.21 \ --bfile /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.21 \ --annot all_da_open_results/train_models/clusters_12-cluster_5.21.annot.gz \ --l2 Beginning analysis at Wed Nov 1 00:07:22 2017 Read list of 138712 SNPs from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.21.bim Read 1 annotations for 138712 SNPs from all_da_open_results/train_models/clusters_12-cluster_5.21.annot.gz Read list of 489 individuals from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.21.fam Reading genotypes from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.21.bed Estimating LD Score. Reading list of 19331 SNPs for which to print LD Scores from /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.21.snp After merging with --print-snps, LD Scores for 16993 SNPs will be printed. Writing LD Scores for 16993 SNPs to all_da_open_results/train_models/clusters_12-cluster_5.21.l2.ldscore.gz Summary of LD Scores in all_da_open_results/train_models/clusters_12-cluster_5.21.l2.ldscore.gz MAF L2 mean 0.2398 0.0044 std 0.1429 0.0958 min 0.0051 -0.0159 25% 0.1155 0.0000 50% 0.2290 0.0000 75% 0.3640 0.0000 max 0.5000 3.8985 MAF/LD Score Correlation Matrix MAF L2 MAF 1.0000 0.0217 L2 0.0217 1.0000 Annotation Correlation Matrix SPECIFIC_PEAK_INTERSECT SPECIFIC_PEAK_INTERSECT 1.0 Annotation Matrix Column Sums SPECIFIC_PEAK_INTERSECT 11 Summary of Annotation Matrix Row Sums count 1.3871e+05 mean 7.9301e-05 std 8.9048e-03 min 0.0000e+00 25% 0.0000e+00 50% 0.0000e+00 75% 0.0000e+00 max 1.0000e+00 Analysis finished at Wed Nov 1 00:08:51 2017 Total time elapsed: 1.0m:28.56s