********************************************************************* * LD Score Regression (LDSC) * Version 1.0.0 * (C) 2014-2015 Brendan Bulik-Sullivan and Hilary Finucane * Broad Institute of MIT and Harvard / MIT Department of Mathematics * GNU General Public License v3 ********************************************************************* Call: ./ldsc.py \ --print-snps /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.12.snp \ --ld-wind-cm 1.0 \ --out all_da_open_results/train_models/clusters_16-cluster_3.12 \ --bfile /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.12 \ --annot all_da_open_results/train_models/clusters_16-cluster_3.12.annot.gz \ --l2 Beginning analysis at Tue Oct 31 22:04:18 2017 Read list of 480110 SNPs from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.12.bim Read 1 annotations for 480110 SNPs from all_da_open_results/train_models/clusters_16-cluster_3.12.annot.gz Read list of 489 individuals from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.12.fam Reading genotypes from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.12.bed Estimating LD Score. Reading list of 68635 SNPs for which to print LD Scores from /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.12.snp After merging with --print-snps, LD Scores for 58127 SNPs will be printed. Writing LD Scores for 58127 SNPs to all_da_open_results/train_models/clusters_16-cluster_3.12.l2.ldscore.gz Summary of LD Scores in all_da_open_results/train_models/clusters_16-cluster_3.12.l2.ldscore.gz MAF L2 mean 0.2320 0.2584 std 0.1438 0.7334 min 0.0051 -0.0652 25% 0.1063 0.0000 50% 0.2198 0.0125 75% 0.3548 0.1292 max 0.5000 12.4654 MAF/LD Score Correlation Matrix MAF L2 MAF 1.0000 0.0297 L2 0.0297 1.0000 Annotation Correlation Matrix SPECIFIC_PEAK_INTERSECT SPECIFIC_PEAK_INTERSECT 1.0 Annotation Matrix Column Sums SPECIFIC_PEAK_INTERSECT 1277 Summary of Annotation Matrix Row Sums count 480110.0000 mean 0.0027 std 0.0515 min 0.0000 25% 0.0000 50% 0.0000 75% 0.0000 max 1.0000 Analysis finished at Tue Oct 31 23:14:32 2017 Total time elapsed: 1.0h:10.0m:14.07s