********************************************************************* * LD Score Regression (LDSC) * Version 1.0.0 * (C) 2014-2015 Brendan Bulik-Sullivan and Hilary Finucane * Broad Institute of MIT and Harvard / MIT Department of Mathematics * GNU General Public License v3 ********************************************************************* Call: ./ldsc.py \ --print-snps /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.9.snp \ --ld-wind-cm 1.0 \ --out all_da_open_results/train_models/clusters_18-cluster_2.9 \ --bfile /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.9 \ --annot all_da_open_results/train_models/clusters_18-cluster_2.9.annot.gz \ --l2 Beginning analysis at Tue Oct 31 20:53:13 2017 Read list of 438106 SNPs from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.9.bim Read 1 annotations for 438106 SNPs from all_da_open_results/train_models/clusters_18-cluster_2.9.annot.gz Read list of 489 individuals from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.9.fam Reading genotypes from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.9.bed Estimating LD Score. Reading list of 63706 SNPs for which to print LD Scores from /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.9.snp After merging with --print-snps, LD Scores for 55885 SNPs will be printed. Writing LD Scores for 55885 SNPs to all_da_open_results/train_models/clusters_18-cluster_2.9.l2.ldscore.gz Summary of LD Scores in all_da_open_results/train_models/clusters_18-cluster_2.9.l2.ldscore.gz MAF L2 mean 0.2343 0.5734 std 0.1436 1.4042 min 0.0051 -0.1513 25% 0.1084 0.0021 50% 0.2239 0.0589 75% 0.3558 0.4190 max 0.5000 17.7040 MAF/LD Score Correlation Matrix MAF L2 MAF 1.0000 0.0674 L2 0.0674 1.0000 Annotation Correlation Matrix SPECIFIC_PEAK_INTERSECT SPECIFIC_PEAK_INTERSECT 1.0 Annotation Matrix Column Sums SPECIFIC_PEAK_INTERSECT 2753 Summary of Annotation Matrix Row Sums count 438106.0000 mean 0.0063 std 0.0790 min 0.0000 25% 0.0000 50% 0.0000 75% 0.0000 max 1.0000 Analysis finished at Tue Oct 31 22:14:53 2017 Total time elapsed: 1.0h:21.0m:40.03s