********************************************************************* * LD Score Regression (LDSC) * Version 1.0.0 * (C) 2014-2015 Brendan Bulik-Sullivan and Hilary Finucane * Broad Institute of MIT and Harvard / MIT Department of Mathematics * GNU General Public License v3 ********************************************************************* Call: ./ldsc.py \ --print-snps /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.8.snp \ --ld-wind-cm 1.0 \ --out all_da_open_results/train_models/clusters_18-cluster_3.8 \ --bfile /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.8 \ --annot all_da_open_results/train_models/clusters_18-cluster_3.8.annot.gz \ --l2 Beginning analysis at Tue Oct 31 20:20:05 2017 Read list of 549971 SNPs from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.8.bim Read 1 annotations for 549971 SNPs from all_da_open_results/train_models/clusters_18-cluster_3.8.annot.gz Read list of 489 individuals from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.8.fam Reading genotypes from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.8.bed Estimating LD Score. Reading list of 75345 SNPs for which to print LD Scores from /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.8.snp After merging with --print-snps, LD Scores for 65167 SNPs will be printed. Writing LD Scores for 65167 SNPs to all_da_open_results/train_models/clusters_18-cluster_3.8.l2.ldscore.gz Summary of LD Scores in all_da_open_results/train_models/clusters_18-cluster_3.8.l2.ldscore.gz MAF L2 mean 0.2368 0.2734 std 0.1438 0.7100 min 0.0051 -0.0582 25% 0.1094 0.0000 50% 0.2270 0.0277 75% 0.3599 0.1810 max 0.5000 11.0010 MAF/LD Score Correlation Matrix MAF L2 MAF 1.0000 0.0628 L2 0.0628 1.0000 Annotation Correlation Matrix SPECIFIC_PEAK_INTERSECT SPECIFIC_PEAK_INTERSECT 1.0 Annotation Matrix Column Sums SPECIFIC_PEAK_INTERSECT 1284 Summary of Annotation Matrix Row Sums count 549971.0000 mean 0.0023 std 0.0483 min 0.0000 25% 0.0000 50% 0.0000 75% 0.0000 max 1.0000 Analysis finished at Tue Oct 31 22:32:34 2017 Total time elapsed: 2.0h:12.0m:29.66s