********************************************************************* * LD Score Regression (LDSC) * Version 1.0.0 * (C) 2014-2015 Brendan Bulik-Sullivan and Hilary Finucane * Broad Institute of MIT and Harvard / MIT Department of Mathematics * GNU General Public License v3 ********************************************************************* Call: ./ldsc.py \ --print-snps /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.12.snp \ --ld-wind-cm 1.0 \ --out all_da_open_results/train_models/clusters_2-cluster_1.12 \ --bfile /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.12 \ --annot all_da_open_results/train_models/clusters_2-cluster_1.12.annot.gz \ --l2 Beginning analysis at Tue Oct 31 22:04:37 2017 Read list of 480110 SNPs from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.12.bim Read 1 annotations for 480110 SNPs from all_da_open_results/train_models/clusters_2-cluster_1.12.annot.gz Read list of 489 individuals from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.12.fam Reading genotypes from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.12.bed Estimating LD Score. Reading list of 68635 SNPs for which to print LD Scores from /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.12.snp After merging with --print-snps, LD Scores for 58127 SNPs will be printed. Writing LD Scores for 58127 SNPs to all_da_open_results/train_models/clusters_2-cluster_1.12.l2.ldscore.gz Summary of LD Scores in all_da_open_results/train_models/clusters_2-cluster_1.12.l2.ldscore.gz MAF L2 mean 0.2320 1.1120 std 0.1438 1.9569 min 0.0051 -0.1082 25% 0.1063 0.0248 50% 0.2198 0.2417 75% 0.3548 1.3575 max 0.5000 17.6748 MAF/LD Score Correlation Matrix MAF L2 MAF 1.0000 0.0483 L2 0.0483 1.0000 Annotation Correlation Matrix SPECIFIC_PEAK_INTERSECT SPECIFIC_PEAK_INTERSECT 1.0 Annotation Matrix Column Sums SPECIFIC_PEAK_INTERSECT 5058 Summary of Annotation Matrix Row Sums count 480110.0000 mean 0.0105 std 0.1021 min 0.0000 25% 0.0000 50% 0.0000 75% 0.0000 max 1.0000 Analysis finished at Tue Oct 31 23:59:42 2017 Total time elapsed: 1.0h:55.0m:5.25s