********************************************************************* * LD Score Regression (LDSC) * Version 1.0.0 * (C) 2014-2015 Brendan Bulik-Sullivan and Hilary Finucane * Broad Institute of MIT and Harvard / MIT Department of Mathematics * GNU General Public License v3 ********************************************************************* Call: ./ldsc.py \ --print-snps /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.21.snp \ --ld-wind-cm 1.0 \ --out all_da_open_results/train_models/clusters_22-cluster_3.21 \ --bfile /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.21 \ --annot all_da_open_results/train_models/clusters_22-cluster_3.21.annot.gz \ --l2 Beginning analysis at Wed Nov 1 00:03:51 2017 Read list of 138712 SNPs from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.21.bim Read 1 annotations for 138712 SNPs from all_da_open_results/train_models/clusters_22-cluster_3.21.annot.gz Read list of 489 individuals from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.21.fam Reading genotypes from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.21.bed Estimating LD Score. Reading list of 19331 SNPs for which to print LD Scores from /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.21.snp After merging with --print-snps, LD Scores for 16993 SNPs will be printed. Writing LD Scores for 16993 SNPs to all_da_open_results/train_models/clusters_22-cluster_3.21.l2.ldscore.gz Summary of LD Scores in all_da_open_results/train_models/clusters_22-cluster_3.21.l2.ldscore.gz MAF L2 mean 0.2398 0.1086 std 0.1429 0.5175 min 0.0051 -0.0430 25% 0.1155 0.0000 50% 0.2290 0.0000 75% 0.3640 0.0184 max 0.5000 9.6601 MAF/LD Score Correlation Matrix MAF L2 MAF 1.0000 0.0187 L2 0.0187 1.0000 Annotation Correlation Matrix SPECIFIC_PEAK_INTERSECT SPECIFIC_PEAK_INTERSECT 1.0 Annotation Matrix Column Sums SPECIFIC_PEAK_INTERSECT 142 Summary of Annotation Matrix Row Sums count 138712.000 mean 0.001 std 0.032 min 0.000 25% 0.000 50% 0.000 75% 0.000 max 1.000 Analysis finished at Wed Nov 1 00:12:29 2017 Total time elapsed: 8.0m:38.41s