********************************************************************* * LD Score Regression (LDSC) * Version 1.0.0 * (C) 2014-2015 Brendan Bulik-Sullivan and Hilary Finucane * Broad Institute of MIT and Harvard / MIT Department of Mathematics * GNU General Public License v3 ********************************************************************* Call: ./ldsc.py \ --print-snps /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.5.snp \ --ld-wind-cm 1.0 \ --out all_da_open_results/train_models/clusters_24-cluster_1.5 \ --bfile /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.5 \ --annot all_da_open_results/train_models/clusters_24-cluster_1.5.annot.gz \ --l2 Beginning analysis at Tue Oct 31 18:51:05 2017 Read list of 633015 SNPs from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.5.bim Read 1 annotations for 633015 SNPs from all_da_open_results/train_models/clusters_24-cluster_1.5.annot.gz Read list of 489 individuals from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.5.fam Reading genotypes from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.5.bed Estimating LD Score. Reading list of 88059 SNPs for which to print LD Scores from /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.5.snp After merging with --print-snps, LD Scores for 74950 SNPs will be printed. Writing LD Scores for 74950 SNPs to all_da_open_results/train_models/clusters_24-cluster_1.5.l2.ldscore.gz Summary of LD Scores in all_da_open_results/train_models/clusters_24-cluster_1.5.l2.ldscore.gz MAF L2 mean 0.2353 0.3279 std 0.1428 0.8098 min 0.0051 -0.0964 25% 0.1104 0.0000 50% 0.2260 0.0250 75% 0.3558 0.2001 max 0.5000 16.7433 MAF/LD Score Correlation Matrix MAF L2 MAF 1.0000 0.0503 L2 0.0503 1.0000 Annotation Correlation Matrix SPECIFIC_PEAK_INTERSECT SPECIFIC_PEAK_INTERSECT 1.0 Annotation Matrix Column Sums SPECIFIC_PEAK_INTERSECT 1920 Summary of Annotation Matrix Row Sums count 633015.000 mean 0.003 std 0.055 min 0.000 25% 0.000 50% 0.000 75% 0.000 max 1.000 Analysis finished at Tue Oct 31 21:14:49 2017 Total time elapsed: 2.0h:23.0m:44.18s