********************************************************************* * LD Score Regression (LDSC) * Version 1.0.0 * (C) 2014-2015 Brendan Bulik-Sullivan and Hilary Finucane * Broad Institute of MIT and Harvard / MIT Department of Mathematics * GNU General Public License v3 ********************************************************************* Call: ./ldsc.py \ --print-snps /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.2.snp \ --ld-wind-cm 1.0 \ --out all_da_open_results/train_models/clusters_30-cluster_2.2 \ --bfile /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.2 \ --annot all_da_open_results/train_models/clusters_30-cluster_2.2.annot.gz \ --l2 Beginning analysis at Tue Oct 31 17:27:11 2017 Read list of 839590 SNPs from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.2.bim Read 1 annotations for 839590 SNPs from all_da_open_results/train_models/clusters_30-cluster_2.2.annot.gz Read list of 489 individuals from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.2.fam Reading genotypes from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.2.bed Estimating LD Score. Reading list of 116575 SNPs for which to print LD Scores from /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.2.snp After merging with --print-snps, LD Scores for 100038 SNPs will be printed. Writing LD Scores for 100038 SNPs to all_da_open_results/train_models/clusters_30-cluster_2.2.l2.ldscore.gz Summary of LD Scores in all_da_open_results/train_models/clusters_30-cluster_2.2.l2.ldscore.gz MAF L2 mean 0.2371 0.0111 std 0.1439 0.1684 min 0.0051 -0.0320 25% 0.1115 0.0000 50% 0.2280 0.0000 75% 0.3609 0.0000 max 0.5000 11.0173 MAF/LD Score Correlation Matrix MAF L2 MAF 1.0000 0.0191 L2 0.0191 1.0000 Annotation Correlation Matrix SPECIFIC_PEAK_INTERSECT SPECIFIC_PEAK_INTERSECT 1.0 Annotation Matrix Column Sums SPECIFIC_PEAK_INTERSECT 78 Summary of Annotation Matrix Row Sums count 8.3959e+05 mean 9.2902e-05 std 9.6382e-03 min 0.0000e+00 25% 0.0000e+00 50% 0.0000e+00 75% 0.0000e+00 max 1.0000e+00 Analysis finished at Tue Oct 31 17:53:00 2017 Total time elapsed: 25.0m:49.09s