********************************************************************* * LD Score Regression (LDSC) * Version 1.0.0 * (C) 2014-2015 Brendan Bulik-Sullivan and Hilary Finucane * Broad Institute of MIT and Harvard / MIT Department of Mathematics * GNU General Public License v3 ********************************************************************* Call: ./ldsc.py \ --print-snps /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.17.snp \ --ld-wind-cm 1.0 \ --out all_da_open_results/train_models/clusters_4-cluster_3.17 \ --bfile /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.17 \ --annot all_da_open_results/train_models/clusters_4-cluster_3.17.annot.gz \ --l2 Beginning analysis at Tue Oct 31 23:26:52 2017 Read list of 269222 SNPs from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.17.bim Read 1 annotations for 269222 SNPs from all_da_open_results/train_models/clusters_4-cluster_3.17.annot.gz Read list of 489 individuals from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.17.fam Reading genotypes from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.17.bed Estimating LD Score. Reading list of 38396 SNPs for which to print LD Scores from /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.17.snp After merging with --print-snps, LD Scores for 32315 SNPs will be printed. Writing LD Scores for 32315 SNPs to all_da_open_results/train_models/clusters_4-cluster_3.17.l2.ldscore.gz Summary of LD Scores in all_da_open_results/train_models/clusters_4-cluster_3.17.l2.ldscore.gz MAF L2 mean 0.2414 1.8969 std 0.1449 4.1446 min 0.0051 -0.1347 25% 0.1135 0.0207 50% 0.2352 0.3714 75% 0.3671 2.1165 max 0.5000 43.3994 MAF/LD Score Correlation Matrix MAF L2 MAF 1.0000 0.0784 L2 0.0784 1.0000 Annotation Correlation Matrix SPECIFIC_PEAK_INTERSECT SPECIFIC_PEAK_INTERSECT 1.0 Annotation Matrix Column Sums SPECIFIC_PEAK_INTERSECT 4447 Summary of Annotation Matrix Row Sums count 269222.0000 mean 0.0165 std 0.1275 min 0.0000 25% 0.0000 50% 0.0000 75% 0.0000 max 1.0000 Analysis finished at Wed Nov 1 00:11:50 2017 Total time elapsed: 44.0m:58.5s