********************************************************************* * LD Score Regression (LDSC) * Version 1.0.0 * (C) 2014-2015 Brendan Bulik-Sullivan and Hilary Finucane * Broad Institute of MIT and Harvard / MIT Department of Mathematics * GNU General Public License v3 ********************************************************************* Call: ./ldsc.py \ --print-snps /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.11.snp \ --ld-wind-cm 1.0 \ --out all_da_open_results/train_models/clusters_5-cluster_3.11 \ --bfile /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.11 \ --annot all_da_open_results/train_models/clusters_5-cluster_3.11.annot.gz \ --l2 Beginning analysis at Tue Oct 31 21:33:22 2017 Read list of 493922 SNPs from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.11.bim Read 1 annotations for 493922 SNPs from all_da_open_results/train_models/clusters_5-cluster_3.11.annot.gz Read list of 489 individuals from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.11.fam Reading genotypes from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.11.bed Estimating LD Score. Reading list of 71092 SNPs for which to print LD Scores from /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.11.snp After merging with --print-snps, LD Scores for 61027 SNPs will be printed. Writing LD Scores for 61027 SNPs to all_da_open_results/train_models/clusters_5-cluster_3.11.l2.ldscore.gz Summary of LD Scores in all_da_open_results/train_models/clusters_5-cluster_3.11.l2.ldscore.gz MAF L2 mean 0.2389 1.2671 std 0.1430 2.3008 min 0.0051 -0.1191 25% 0.1145 0.0694 50% 0.2301 0.3885 75% 0.3609 1.4846 max 0.5000 21.5835 MAF/LD Score Correlation Matrix MAF L2 MAF 1.0000 0.0438 L2 0.0438 1.0000 Annotation Correlation Matrix SPECIFIC_PEAK_INTERSECT SPECIFIC_PEAK_INTERSECT 1.0 Annotation Matrix Column Sums SPECIFIC_PEAK_INTERSECT 5457 Summary of Annotation Matrix Row Sums count 493922.0000 mean 0.0110 std 0.1045 min 0.0000 25% 0.0000 50% 0.0000 75% 0.0000 max 1.0000 Analysis finished at Tue Oct 31 22:53:34 2017 Total time elapsed: 1.0h:20.0m:11.78s