********************************************************************* * LD Score Regression (LDSC) * Version 1.0.0 * (C) 2014-2015 Brendan Bulik-Sullivan and Hilary Finucane * Broad Institute of MIT and Harvard / MIT Department of Mathematics * GNU General Public License v3 ********************************************************************* Call: ./ldsc.py \ --print-snps /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.2.snp \ --ld-wind-cm 1.0 \ --out all_da_open_results/train_models/clusters_5-cluster_4.2 \ --bfile /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.2 \ --annot all_da_open_results/train_models/clusters_5-cluster_4.2.annot.gz \ --l2 Beginning analysis at Tue Oct 31 17:26:35 2017 Read list of 839590 SNPs from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.2.bim Read 1 annotations for 839590 SNPs from all_da_open_results/train_models/clusters_5-cluster_4.2.annot.gz Read list of 489 individuals from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.2.fam Reading genotypes from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.2.bed Estimating LD Score. Reading list of 116575 SNPs for which to print LD Scores from /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.2.snp After merging with --print-snps, LD Scores for 100038 SNPs will be printed. Writing LD Scores for 100038 SNPs to all_da_open_results/train_models/clusters_5-cluster_4.2.l2.ldscore.gz Summary of LD Scores in all_da_open_results/train_models/clusters_5-cluster_4.2.l2.ldscore.gz MAF L2 mean 0.2371 0.8212 std 0.1439 1.3297 min 0.0051 -0.0931 25% 0.1115 0.0718 50% 0.2280 0.2877 75% 0.3609 1.0000 max 0.5000 17.9141 MAF/LD Score Correlation Matrix MAF L2 MAF 1.000 0.076 L2 0.076 1.000 Annotation Correlation Matrix SPECIFIC_PEAK_INTERSECT SPECIFIC_PEAK_INTERSECT 1.0 Annotation Matrix Column Sums SPECIFIC_PEAK_INTERSECT 6049 Summary of Annotation Matrix Row Sums count 839590.0000 mean 0.0072 std 0.0846 min 0.0000 25% 0.0000 50% 0.0000 75% 0.0000 max 1.0000 Analysis finished at Tue Oct 31 19:02:52 2017 Total time elapsed: 1.0h:36.0m:17.83s