********************************************************************* * LD Score Regression (LDSC) * Version 1.0.0 * (C) 2014-2015 Brendan Bulik-Sullivan and Hilary Finucane * Broad Institute of MIT and Harvard / MIT Department of Mathematics * GNU General Public License v3 ********************************************************************* Call: ./ldsc.py \ --print-snps /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.5.snp \ --ld-wind-cm 1.0 \ --out all_da_open_results/train_models/clusters_5-cluster_5.5 \ --bfile /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.5 \ --annot all_da_open_results/train_models/clusters_5-cluster_5.5.annot.gz \ --l2 Beginning analysis at Tue Oct 31 18:43:13 2017 Read list of 633015 SNPs from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.5.bim Read 1 annotations for 633015 SNPs from all_da_open_results/train_models/clusters_5-cluster_5.5.annot.gz Read list of 489 individuals from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.5.fam Reading genotypes from /net/gs/vol1/home/ajh24/bin/ldsc/1000G_EUR_Phase3_plink/1000G.EUR.QC.5.bed Estimating LD Score. Reading list of 88059 SNPs for which to print LD Scores from /net/gs/vol1/home/ajh24/bin/ldsc/hapmap3_snps/hm.5.snp After merging with --print-snps, LD Scores for 74950 SNPs will be printed. Writing LD Scores for 74950 SNPs to all_da_open_results/train_models/clusters_5-cluster_5.5.l2.ldscore.gz Summary of LD Scores in all_da_open_results/train_models/clusters_5-cluster_5.5.l2.ldscore.gz MAF L2 mean 0.2353 0.3785 std 0.1428 0.8531 min 0.0051 -0.0701 25% 0.1104 0.0024 50% 0.2260 0.0493 75% 0.3558 0.2967 max 0.5000 11.7690 MAF/LD Score Correlation Matrix MAF L2 MAF 1.0000 0.0658 L2 0.0658 1.0000 Annotation Correlation Matrix SPECIFIC_PEAK_INTERSECT SPECIFIC_PEAK_INTERSECT 1.0 Annotation Matrix Column Sums SPECIFIC_PEAK_INTERSECT 2307 Summary of Annotation Matrix Row Sums count 633015.0000 mean 0.0036 std 0.0603 min 0.0000 25% 0.0000 50% 0.0000 75% 0.0000 max 1.0000 Analysis finished at Tue Oct 31 21:06:17 2017 Total time elapsed: 2.0h:23.0m:4.76s