featured preprints (work led or co-led by our lab)

Lalanne et al. Extensive length and homology dependent chimerism in pool-packaged AAV libraries.
bioRxiv 2025.01.14.632594
Posted January 15, 2025

Ho et al. Linking candidate causal autoimmune variants to T cell networks using genetic and epigenetic screens in primary human T cells.
bioRxiv 2024.10.07.617092
Posted January 15, 2025

Seidel et al. Sciphy: A Bayesian phylogenetic framework using sequential genetic lineage tracing data.
bioRxiv 2024.10.01.615771
Posted October 3, 2024

McDiarmid et al. Diversified, miniaturized and ancestral parts for mammalian genome engineering and molecular recording.
bioRxiv 2024.09.30.615957
Posted October 1, 2024

Garge et al. The proteomic landscape and temporal dynamics of mammalian gastruloid development.
bioRxiv 2024.09.05.609098
Posted September 18, 2024

Baron et al. Leukemia-derived apelin selects endothelial niche clones to promote tumorigenesis.
bioRxiv 2024.09.09.612077
Posted September 13, 2024

Liao, Kottapalli et al. Optics-free reconstruction of 2D images via DNA barcode proximity graphs.
bioRxiv 2024.08.06.606834
Posted August 8, 2024

Zang et al. Multi-condition and multi-modal temporal profile inference during mouse embryonic development.
bioRxiv 2024.03.03.583179
Posted March 4, 2024

Casto et al. SARS-CoV-2 diversity and transmission on a university campus across two academic years during the pandemic.
medRxiv 2024.02.29.24303285
Posted March 2, 2024

Zang et al. Cross-species imputation and comparison of single-cell transcriptomic profiles.
bioRxiv 2023.10.19.563173
Posted August 12, 2024

Chardon et al. A multiplex, prime editing framework for identifying drug resistance variants at scale.
bioRxiv 2023.07.27.550902
Posted July 30, 2023

Fang et al. CTCF-mediated insulation and chromatin environment modulate Car5b escape from X inactivation.
bioRxiv 2023.05.04.539469
Posted May 4, 2023

Barbosa et al. High Density Domain-Focused CRISPR Screens Reveal Novel Epigenetic Regulators of HOX/MEIS Activation in Acute Myeloid Leukemia.
bioRxiv 2022.12.12.519332
Posted March 6, 2023

Minkina et al. Tethering distinct molecular profiles of single cells by their lineage histories to investigate sources of cell state heterogeneity.
bioRxiv 2022.05.12.491602
Posted May 12, 2022

Burstein et al. Interactions among 17 respiratory pathogens: a cross-sectional study using clinical and community surveillance data.
bioRxiv 2022.02.04.22270474
Posted February 6, 2022

Bedford et al. Viral genome sequencing places White House COVID-19 outbreak into phylogenetic context.
medRxiv 2022.05.12.491602
Posted November 01, 2020

Calderon et al. TransMPRA: A framework for assaying the role of many trans-acting factors at many enhancers.
bioRxiv 2020.09.30.321323
Posted October 01, 2020

Guo et al. Rapid cost-effective viral genome sequencing by V-seq.
bioRxiv 2020.08.15.252510
Posted August 15, 2020

Deng et al. A Genomic Survey of SARS-CoV-2 Reveals Multiple Introductions into Northern California without a Predominant Lineage.
bioRxiv 2020.03.27.20044925
Posted March 30, 2020